Lisinopril pharmacokinetics in chronic renal failure.
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics of ropivacaine in patients with chronic renal failure.
BACKGROUND As ropivacaine and its metabolites are excreted by the kidneys, we studied their disposition in subjects with renal dysfunction. METHODS Twenty patients with moderate or severe renal insufficiency and 10 healthy volunteers received ropivacaine 1 mg kg(-1) i.v. over 30 min. The concentrations of ropivacaine and its main metabolites, pipecoloxylidide (PPX) and 3-hydroxy-ropivacaine, ...
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Background and aim: Pruritus is a common disabling problem in patients with end stage renal disease. Several studies has recorded the relation between pruritus with hemodialysis in chronic renal failure (CRF) patients. This study was designed to evaluate the effect of hemodialysis on pruritus of patients with CRF.Materials and Methods: After recording the demographic data and the diagnosis of d...
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Chronic renal failure is an uncommon disease in children with some difference in the etiology in different countries. In this study on 180 children (From 1987 to 1997 in Shiraz) with age range of 3 months to 15 years (mean 8.6±4.2 years). The male to female ratio was 1. 57: 1. The etiology of chronic renal failure in decreasing order of frequency were: reflux nephropathy (25 % ) , glbmerular di...
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The pharmacokinetics of ofloxacin were investigated in 12 normal subjects and 21 uremic patients after the administration of a single oral 200-mg dose. An open three-compartment body model was used to calculate ofloxacin pharmacokinetic parameters. In healthy subjects, the peak plasma level averaged 2.24 +/- 0.90 micrograms/ml and was obtained at 0.83 +/- 0.31 h. The absorption rate constant wa...
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Background: Metabolic disturbances and dyslipidemia are among the most important medical problems in human society. Their effects on the mortality of coronary heart disease (CHD) have lead to many investigations about them. Materials and Methods: An epidemiologic cross-sectional study was carried out on 10136 persons selected randomly in Tehran urban district 13 with a minimum age of 20 years ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1988
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1988.tb05258.x